The answer
Although it is not mentioned in the Holy Bible, yet our liturgical tradition records that in the Last Supper, our Lord used wine mingled with water. The Church Fathers had plenty to say about this matter. Traditon as well as our Lord’s passion on the cross tell us that the wine- to- be blood is to be mixed with water. From the stroke of the lance there flowed from His side blood and water. "But one of the soldiers pierced His side with a spear, and immediately blood and water came out" (John 19:34).Answered by His Eminence Metropolitan Youssef (opens in a new tab)