The answer
Not at all. If the Lord has not granted the blessing of child bearing to the couple, it is because He wants them to be parents for many, many spiritual children, such as the orphans.
H.G. Bishop Moussa
H.G. Bishop Moussa · Youth Concerns · 120
Faith Q&A › Youth Concerns › Relationships and Marriage
If a couple are unable to have children, does it mean their marriage is not blessed by God?
H.G. Bishop Moussa, Bishop of Youth, Youth Concerns (Questions & Answers). Compiled by Lisa Agaybi. Coptic Orthodox Patriarchate, Bishopric of Youth Bookstore.