The answer
The Church remained one until 451, when the tragic Council of Chalcedon convened. The One Church was divided over the nature of the Master Christ into East and West.
In 1054, the Byzantine churches (includes Greeks, Russians, etc.) and the Western Catholic Church separated over the addition of the clause “and the Son” to the Creed.51
In the sixteenth century, Protestantism appeared as a reaction to Catholic extremes. The famous Reformation was led by Martin Luther.
His Holiness Pope Tawadros II
Notes
51 Translator’s note: Traditionally referred to as the Filioque; “We believe in the Holy Spirit, the Lord, the Giver of Life, Who proceeds from the Father and the Son” (emphasis mine).
Pope Tawadros II, My Faith: A Series of Dialogues on the Creed (Coptic Orthodox Patriarchate, 2014), 142–143.

